Sr Associate Scientist AFP

Location: South San Francisco, CA
Date Posted: 11-30-2017
Day to Day Responsibilities:     
  • Mammalian expression of recombinant gene constructs
  • Perform small to large-scale protein production runs for protein purification and carry out expression characterization such as gel electrophoresis and Western-blot.
  • Operate, and when appropriate optimize, medium to large scale production processes.
  • Recording data in notebooks and laboratory databases as per company policies in a complete, accurate, and timely manner is a critical responsibility
  • Present data to project teams as needed
  • Participate in general lab maintenance including maintaining laboratory supplies and equipment
  • Work closely with different groups across functions, collaborate within a highly multidisciplinary environment
Summary:
To perform experiments, organize data and analyze results under minimal supervision. With minimal supervision, plans, conducts or monitors experiments, records and organizes data, analyses results, generates robust and reliable data and/or Ensures that contracted studies are conducted in compliance with the respective protocol and applicable guidelines and regulations.Responsibilities include:? Monitors or follows established experimental design and protocols and performs routine tasks and studies to obtain reproducible and reliable results with limited supervision? Plans, monitors or conducts, analyzes and records experiments, and provides interpretation of data? Effectively transfers experimental methods from literature to the lab and makes modifications as necessary? Develops and implements new protocols with moderate review ? Engages coworkers in scientific discussions? Communicates data and interpretation to work group? Skilled at developing systems to ensure quality data? Skilled and/or knowledgeable in the use of standard laboratory equipment and with one or more major laboratory instruments/techniques ? Effectively trouble-shoots equipment and experimental difficulties? Contributes to internal/external reports, papers, presentations, regulatory documents, invention disclosure submissions and/or patents? Participates in department-wide support efforts such as safety, recruiting and committees? May train staff and/or supervise others? Coordinates and organizes resources needed to complete the task? Understands when to seek input and when to make independent judgments

Skills:
  • Degree in Biology, Biochemistry or Analytical Chemistry
  • Experience in a Biopharmaceutical working environment
Basic Qualifications
Master’s degree & 5 years of scientific experience
OR
Bachelor’s degree & 7 years of scientific experience

Preferred Qualifications
  • MS in Cell Biology, Biochemistry, Molecular Biology, or related field, with a minimum of 5 years laboratory experience with cell culture, preferably in an industry environment
  • Extensive experience with recombinant protein expression in mammalian cell systems is a must
  • Protein expression analysis techniques (e.g. gel electrophoresis, Western Blot, Octet) are required
  • Hands-on experience with WAVE and/or tank bioreactors is preferred
  • Working knowledge in molecular biology and protein biochemistry is preferred
  • Hands-on experience with lab automation is a plus
  • Ability to identify, develop and implement scientific solutions to practical problems
  • Attention to details and strong problem solving skills
  • Excellent communication, collaboration, and organizational skills are essential.
  • Must be a motivated team player with commitment to quality and timeline.

"This posting is for Contingent Worker, not an FTE"
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