logo

View all jobs

Senior Scientist - Computational Biology, Biomarker Analysis

South San Francisco, CA
“This Company requires all staff, staff augmentation external workers, and certain other external workers, in the United States and  puerto rico vaccinated from COVID 19 as a condition of assignment at this company. In accordance with applicable law, this company will provide reasonable accommodations staff augmentation external workers qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship this company, its operations, or its staff.”                                                        

Top 3 Must Have Skills                                                                            
Experience with working with clinical data analysis
Must have knowledge of programming; Python or R
Experience with machine learning

Day to Day Responsibilities:                                        
Support the development of clinical biomarkers supporting Amgen programs through the formulation and execution of biomarker data analysis
Perform assessment of biochemical coverage, patient stratification, indication selection in Amgen’s early and late clinical development programs and discovery of clinical insights at asset and portfolio levels through the application of knowledge discovery and data mining techniques
Develop translational informatics analysis methods to enable the analysis of NGS data/Epigenomics assays/single-cell assays from clinical trials
Develop translational informatics analysis workflows in a high-content, multi-omics, multi-modal data domain encompassing genomics, transcriptomics, proteomics, metabolomics and epigenomics domains
Develop innovative best-practices for the next generation of clinical bioinformatics, such as the utilization of ctDNA-derived tumor burden as a prognostic biomarker/surrogate end point
Work with biologists, especially in immuno-oncology, to leverage information on targeted biological pathways along with development of computational algorithms to manage and mine internal and external genomics and other high-content databases
Provide leadership and expertise to the function in the areas of algorithm development, bioinformatics, data integration & management, visualization, analysis and presentation
May represent the clinical biomarkers & diagnostics team in Amgen program/portfolio teams as a biomarker analysis lead
Interface cross-functionally with the early development teams, assay laboratories, in-vitro diagnostics and biomarker representatives



"This posting is for Contingent Worker, not an FTE"
 

More Openings

Associate
Project Manager

Share This Job

Powered by