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Sr Associate Scientist AFP

South San Francisco, CA
Day to Day Responsibilities:  
  • Mammalian expression of recombinant gene constructs
  • Perform small to large-scale protein production runs for protein purification and carry out expression characterization such as gel electrophoresis and Western-blot.
  • Operate, and when appropriate optimize, medium to large scale production processes.
  • Recording data in notebooks and laboratory databases as per company policies in a complete, accurate, and timely manner is a critical responsibility
  • Present data to project teams as needed
  • Participate in general lab maintenance including maintaining laboratory supplies and equipment
  • Work closely with different groups across functions, collaborate within a highly multidisciplinary environment
  • To perform experiments, organize data and analyze results under minimal supervision. With minimal supervision, plans, conducts or monitors experiments, records and organizes data, analyses results, generates robust and reliable data and/or Ensures that contracted studies are conducted in compliance with the respective protocol and applicable guidelines and regulations.
  • Responsibilities include:
  • Monitors or follows established experimental design and protocols and performs routine tasks and studies to obtain reproducible and reliable results with limited supervision
  • Plans, monitors or conducts, analyzes and records experiments, and provides interpretation of data Effectively transfers experimental methods from literature to the lab and makes modifications as necessary
  • Develops and implements new protocols with moderate review
  • Engages coworkers in scientific discussions
  • Communicates data and interpretation to work group
  • Skilled at developing systems to ensure quality data
  • Skilled and/or knowledgeable in the use of standard laboratory equipment and with one or more major laboratory instruments/techniques
  • Effectively trouble-shoots equipment and experimental difficulties
  • Contributes to internal/external reports, papers, presentations, regulatory documents, invention disclosure submissions and/or patents
  • Participates in department-wide support efforts such as safety, recruiting and committees
  • May train staff and/or supervise others
  • Coordinates and organizes resources needed to complete the task
  • Understands when to seek input and when to make independent judgments
  • Degree in Biology, Biochemistry or Analytical Chemistry
  • Experience in a Biopharmaceutical working environment
Basic Qualifications
Master’s degree & 5 years of scientific experience
Bachelor’s degree & 7 years of scientific experience

Preferred Qualifications
  • MS in Cell Biology, Biochemistry, Molecular Biology, or related field, with a minimum of 5 years laboratory experience with cell culture, preferably in an industry environment
  • Extensive experience with recombinant protein expression in mammalian cell systems is a must
  • Protein expression analysis techniques (e.g. gel electrophoresis, Western Blot, Octet) are required
  • Hands-on experience with WAVE and/or tank bioreactors is preferred
  • Working knowledge in molecular biology and protein biochemistry is preferred
  • Hands-on experience with lab automation is a plus
  • Ability to identify, develop and implement scientific solutions to practical problems
  • Attention to details and strong problem solving skills
  • Excellent communication, collaboration, and organizational skills are essential.
  • Must be a motivated team player with commitment to quality and timeline.
"This posting is for Contingent Worker, not an FTE"
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