Conducting in vivo pharmacology oncology studies (mouse models).
Inoculating tumors subcutaneously, measuring tumors, dosing, blood & tissue collection for PD, PK and efficacy studies.
Working both independently and as part of a team to execute studies and to collect data.
The Department of Oncology at Amgen in South San Francisco is seeking a highly motivated researcher to perform in vivo pharmacology studies aimed at elucidating mechanisms of immune-mediated regulation of tumor growth in order to develop novel immunomodulatory therapies for the treatment of cancer.
Responsibilities will include conducting, analyzing and reporting data for PD, PK and efficacy studies to support the progression of oncology and inflammation research teams.
Must have extensive mouse handling skills, including: In vivo models of cancer; subcutaneous tumor inoculations and measurements; dosing techniques (iv, ip, subQ); blood and tissue (ex. tumor, spleen, lymph nodes, liver) collection. In vitro cell culture and flow cytometry experience is a plus.
Minimum Basic Qualifications
B.S. degree in Physical, Life Sciences or related technical discipline.
Min 2 years' working with mouse in vivo models
Previous drug discovery experience
Research experience with preclinical murine models of cancer & cancer immunotherapy
Hands on experience administering drugs through various routes
Hands on experience with flow cytometry
Computer literacy, especially proficiency with Graphpad Prism, Excel, Powerpoint and Word
Excellent organizational and communication skills, along with the ability to work in a flexible team-oriented environment
"This posting is for Contingent Worker, not an FTE"